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Inflammation

High-Sensitivity C-Reactive Protein test cost

By Elo. Last updated June 2026.

hs-CRP measures low-grade systemic inflammation associated with cardiovascular disease risk. It's one of the most widely ordered inflammation markers.

Below we compare what hs-CRP costs on its own against every testing package we track that includes it, sorted by price. We pulled the standalone figure from a direct-to-consumer lab that runs on the Quest or LabCorp network and checked each bundle against the providers we track, so you can see the cheapest way to get this marker.

How much does a hs-CRP test cost?

hs-CRP costs $71 on its own, or $190–$689 when purchased as a bundle.

Quest (standalone)$71 · lowest priceEmpirical Health$190Superpower$199Vitals Vault$199Parsley Health$275Mito Health$349WHOOP Advanced Labs$349Function Health$365Vitals Vault$399Everlywell$399Marek Health$495InsideTracker$499Marek Health$595LabCorp OnDemand$689
hs-CRP test cost by provider, standalone versus bundles. Lowest price highlighted in green.

Cheapest option: Order hs-CRP on its own. Quest sells a standalone test for $71, which is cheaper than any bundle that includes it.

Standalone price is the all-in consumer cost to order hs-CRP by itself, including a $6 physician service fee. Verified June 2026.

Do medical guidelines recommend a hs-CRP test?

hs-CRP measures inflammation, which cardiology authorities increasingly treat as a risk factor for heart disease that acts independently of cholesterol.

  • Cardiology guidelines. In 2025, the American College of Cardiology issued a scientific statement concluding that inflammation is an independent, treatable contributor to cardiovascular disease, and supporting broad hs-CRP testing in people with and without known heart disease, alongside a standard LDL cholesterol check.
  • Clinical trials. In the landmark JUPITER trial, apparently healthy people with normal LDL cholesterol but elevated hs-CRP who took a statin had about 44% fewer major cardiovascular events than those on placebo, evidence that inflammation flags risk a cholesterol test alone can miss.

Frequently asked questions about hs-CRP testing

What is the cheapest way to get a hs-CRP test?

Order hs-CRP on its own. Quest sells a standalone test for $71, which is cheaper than any bundle that includes it.

Do I need a doctor's order to get a hs-CRP test?

No. The standalone hs-CRP test listed above includes the physician order in its price, so you can buy it online and have your blood drawn without your own doctor. You would only need your own doctor's order if you want to bill the test to insurance.

Is a hs-CRP test covered by insurance?

hs-CRP for heart-risk assessment is not universally covered, especially as a screening test when you have no symptoms, so it is often paid out of pocket (around $71 standalone).

What hs-CRP level is considered high?

For cardiovascular risk, under 1 mg/L is low risk, 1 to 3 mg/L is average, and above 3 mg/L is higher risk. A value above about 10 mg/L usually signals a temporary infection or illness rather than chronic risk, so the test is repeated.

Do I need to fast for an hs-CRP test?

No. hs-CRP does not require fasting. It is best to avoid testing during an active infection, injury, or flare of an inflammatory condition, since that can temporarily raise the result.